Associate Scientist

This role is a contract position. Artis BioSolutions is seeking a motivated Process Development Downstream Associate Scientist to support the development and optimization of purification processes for advanced therapeutic modalities, including adeno-associated viral vectors (AAV), lentiviral vectors (LVV), and extracellular vesicles (EV). The successful candidate will plan and execute laboratory experiments, analyze data, troubleshoot technical challenges, and contribute to process development activities, including continuous processing technologies.

This hands-on, laboratory-based role requires strong problem-solving skills, a collaborative mindset, and flexibility in scheduling to accommodate experimental needs, including occasional weekend work.

Responsibilities- Plan and execute downstream process development experiments for advanced therapeutic modalities, including AAV, LVV, and EV.

• Develop, optimize, and troubleshoot purification processes, including clarification, depth filtration, tangential flow filtration (TFF), and chromatography.
• Support the development and evaluation of continuous and intensified downstream processing technologies.
• Perform laboratory experiments to evaluate process parameters and improve product recovery, purity, yield, and quality.
• Operate, maintain, and troubleshoot downstream processing equipment, including AKTA chromatography systems and TFF systems.
• Collect, analyze, and interpret experimental data, document results, and communicate findings to the project team.
• Prepare technical reports, experimental protocols, and standard operating procedures (SOPs).
• Collaborate with upstream process development, analytical development, and manufacturing teams to support project objectives and technology transfer.
• Maintain accurate laboratory records and ensure compliance with established safety and quality procedures.
• Support laboratory operations, including equipment maintenance, inventory management, and preparation of buffers and solutions.
• Demonstrate flexibility in scheduling to support experimental activities, including occasional weekend work.   Education- Bachelor’s degree in biology, Bioengineering, Biotechnology, Chemical Engineering, or a related scientific discipline with 6+ years of relevant experience, or a master’s degree with 4+ years of relevant experience.   Skills / Knowledge- Demonstrated hands-on experience with downstream purification technologies, including clarification, filtration, and chromatography.
• Proven track record of success in biopharmaceutical process development.
• Strong analytical, troubleshooting, and problem-solving skills, with excellent attention to detail.
• Ability to work independently and collaboratively within a multidisciplinary team.
• Excellent organizational and time-management skills, with the ability to manage multiple priorities.