Engineer

Scholar Rock is delivering muscle-targeted breakthroughs to transform the treatment of spinal muscular atrophy (SMA) and other rare neuromuscular diseases where muscle atrophy remains a critical unmet need.

As a global leader in myostatin biology, a field focused on proteins that regulate muscle mass, the biopharmaceutical company is named for the visual resemblance of a scholar rock to protein structures. Our commitment to unlock fundamentally different treatment approaches is powered by broad application of a proprietary platform, which has developed novel monoclonal antibodies to modulate protein growth factors with extraordinary selectivity. Scholar Rock works every day to create new possibilities for patients through its highly innovative anti-myostatin program, including opportunities in additional rare neuromuscular diseases. Learn more about our neuromuscular franchise at ScholarRock.com and follow @ScholarRock on X and on LinkedIn.

  Summary of Position:

Scholar Rock is seeking a Senior Engineer, Downstream Manufacturing Science & Technology (MSAT), to provide technical leadership for monoclonal antibody downstream manufacturing across a global external manufacturing network. This role serves as the downstream process SME supporting commercial manufacturing, technology transfer, PPQ/process validation, CPV, investigations, change control, regulatory support, and lifecycle management. 

The ideal candidate brings strong downstream biologics process expertise, significant GMP manufacturing experience, sound technical judgment, and the ability to partner effectively with CDMOs and internal Process Development, External Manufacturing, Quality, Regulatory, and Supply Chain teams.  This role is expected to influence cross-functional decision-making and serve as a trusted technical partner across downstream manufacturing activities.

Position Responsibilities

External Manufacturing Support:

• • Provide downstream process oversight for late-stage clinical and commercial manufacturing at CDMOs, including campaign readiness, technical risk assessment, manufacturing planning, and execution support.
  • Serve as Person-in-Plant, as needed, for technology transfer, PPQ/process validation, and clinical/commercial manufacturing activities.
  • Provide timely technical support during critical manufacturing operations, including off-hours support when required.