Scientist

Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.   We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.   GRAIL is headquartered in the Bay Area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.   For more information, please visit grail.com

The Senior Scientist is a scientific and people supervisor responsible for driving platform troubleshooting and assay development while building, leading, and developing a high-performing team of scientists and research associates. This role provides scientific and technical supervision, oversees execution of research activities, establishes team priorities, mentors and develops talent, and collaborates cross-functionally to ensure reliable platform operation and continuous innovation.

This position works on-site full-time, 5 days/week at our office located in Durham, NC

Responsibilities:

• Independently design, plan, and execute experiments to support platform troubleshooting, optimization, and other research objectives.
• Analyze, interpret, and present experimental results to identify root causes of platform performance issues and provide scientifically sound recommendations.
• Develop, optimize, and troubleshoot experimental methods, protocols, and workflows to improve platform performance, robustness, efficiency, and data quality.
• Investigate technical challenges, identify sources of variability, and implement corrective actions to ensure reliable platform operation.
• Provide day-to-day supervision, coaching, performance feedback, and career development for direct reports.
• Establish team priorities, allocate resources, and ensure timely execution of project deliverables.
• Prepare detailed technical reports, presentations, and documentation summarizing troubleshooting investigations, platform performance, and research findings.
• Collaborate with cross-functional teams to resolve platform-related issues and integrate findings into broader research and development strategies.
• Ensure compliance with laboratory safety, quality, and regulatory standards while maintaining platform reliability and operational excellence.