IT Director

ABOUT LAKEFRONT BIOTHERAPEUTICS

Lakefront Biotherapeutics is a global biotech with offices in Belgium, Chicago and San Francisco, focused on building a differentiated immunology and inflammation pipeline to address serious diseases with high unmet medical need. Our pipeline is anchored by T‑cell engager programs, led by a potential first‑in‑class clinical asset and complemented by an exciting preclinical portfolio in autoimmune disease.

Our lead asset is being developed for severe immune‑mediated diseases, while additional preclinical programs expand the long‑term potential of our R&D pipeline. At Lakefront, we focus on advancing programs with strong biological rationale, clear clinical proof of concept and large commercial opportunities.

Are you ready to transform lives and be part of a journey like no other? We are building a company where science, execution, and accountability matter. Rather than layers of hierarchy, we operate with small, empowered teams that work hands‑on across development stages to move programs forward efficiently and thoughtfully.

We are looking for people who want to contribute directly, who are motivated by solving real problems, collaborating across disciplines, and taking ownership from idea to impact. At Lakefront, every role plays a part in shaping the future of medicines that have the potential to make a meaningful difference for patients.

If you are driven to improve the lives of patients, energized by execution, and excited to help build a growing company with a strong balance sheet, we look forward to meeting you.

The Role

The Director of IT runs day-to-day technology operations for Lakefront Bio and leads delivery of the IT roadmap set with the Vice President of IT. This is a hands-on leadership role. You will own end-user services, business application support, and the compliance posture of our systems. You will manage managed service providers (MSPs) and vendors, and you will make sure our GxP-relevant systems stay validated and inspection-ready.

You will work closely with Quality, Regulatory Affairs, CMC and manufacturing, Research and laboratory operations, Clinical Operations, Facilities, and Finance. The right person is comfortable troubleshooting a user escalation in the morning and presenting a validation plan to Quality in the afternoon.

What You'll Do

IT OPERATIONS AND SERVICE DELIVERY

• Manage MSPs, Contractors and IT vendors against defined SLAs, including help desk, onboarding and offboarding, and asset lifecycle.
• Set service standards for end-user support and measure performance against them for your defined location.
• Help to set that standards for service delivery related to ticket queue creations and KPI metrics reporting.