Safety Systems

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.

Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.

The Opportunity:

The Associate Director, Safety Systems, Japan is responsible for providing safety and pharmacovigilance systems expertise to support safety management activities in Japan. The individual will be responsible for ensuring the effective operation and local use of global safety databases and related pharmacovigilance systems, coordinating Japan-specific system requirements and changes, and ensuring appropriate system administration, data quality, documentation, and user support in accordance with applicable Japanese regulations such as GVP/GPSP, company procedures, and global pharmacovigilance/patient safety standards.

The Associate Director, Safety Systems works closely with Global Safety Systems, Global IT, and other Global/Japan Safety Functions and  cross-functional stakeholders to ensure the reliable, compliant, and effective use of safety systems in Japan. The individual also coordinates with CROs, system vendors, and other external partners, supporting system issue resolution, validation and change activities, audit and inspection readiness, and continuous improvement of local safety system operations.

Key Responsibilities:

• Safety System Operations and Global Coordination: Coordinate with Global Safety Systems and relevant global functions to ensure the effective use of global safety databases and related pharmacovigilance systems in Japan.

• Local System Administration and User Access: Manage Japan-specific system administration activities, including user access, user roles, local workflows, and other administrative tasks in accordance with approved procedures and global standards.

• System Data Quality and Controls: Monitor system data integrity and system controls for Japan operations; identify discrepancies or system-related issues and coordinate appropriate investigation and resolution.

• Local Requirements and System Changes: Coordinate Japan-specific business and regulatory requirements for system changes, enhancements, releases, and configuration updates with Global Safety Systems and relevant stakeholders.