Global SOX

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.

Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.

The Opportunity

RevMed is seeking an experienced, collaborative Senior Director, Global SOX to lead and scale the Company’s Sarbanes-Oxley compliance and internal controls program. This role has enterprise-wide governance responsibility for ICFR, ITGCs, ITACs, automated controls, key reports, and controls supporting evolving business processes, systems, commercial readiness, and global expansion.

As a key Controllership leader, this role partners with functions, auditors, and process owners across the United States, Europe, Japan, Canada, and other markets. The leader will establish global SOX governance and practical regional execution, ensuring rigorous compliance while building risk-based, scalable controls that work effectively with business operations.

This role reports to the VP, Finance, Controller, is based at RevMed’s Redwood City headquarters, and works closely with regional Finance, IT, and business teams.

Responsibilities

Global SOX Program Leadership

• Lead RevMed’s global SOX and ICFR program, including annual planning, scoping, risk assessments, walkthroughs, documentation, testing coordination, deficiency evaluation, remediation tracking, and reporting.
• Develop a scalable operating model with centralized governance, consistent standards, clear accountability, and right-sized controls that maintain compliance without unnecessary operational burden.
• Partner with Accounting, SEC Reporting, Technical Accounting, IT, Commercial, Supply Chain, Legal, HR, and regional teams to identify financial reporting risks and ensure controls are well designed, documented, owned, and effective.
• Maintain SOX documentation, including risk and control matrices, narratives, flowcharts, key reports, management review controls, and regional certifications or attestations.
• Provide quarterly and annual SOX updates to the Controller, senior management, and the Audit Committee, including status, key risks, deficiencies, and remediation progress.