Medical Affairs External Funding Operations Manager

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.

Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.

The Opportunity

The Senior Manager, Medical Affairs External Funding Operations will serve as the operational owner of Revolution Medicines' external funding program supporting Medical Affairs objectives, with primary responsibility for the infrastructure, governance processes, systems, and operational strategy that enable compliant and effective management of Independent Medical Education (IME), Patient Advocacy, Charitable Donations, and other applicable external funding activities.

This individual will own and continuously evolve the operational framework supporting the end-to-end funding lifecycle, including request intake, review and governance processes, grants management systems, budget and portfolio tracking, contracting, payment processing, Letters of Agreement (LOAs), program tracking, reporting, and documentation. The Senior Manager will apply independent judgment to identify and resolve complex operational issues, partner with Medical Affairs, Legal, Compliance, Finance, and other stakeholders on matters requiring cross-functional input, and drive scalable process improvements as the external funding program evolves.

As a key partner to Medical Strategy teams and the Medical Affairs Grant Review Committee (GRC), this role will translate external funding data and program activity into actionable reporting and insights that support funding discussions, portfolio visibility, operational planning, and continuous improvement. The Senior Manager will own the operational cadence and materials supporting GRC meetings and maintain visibility into the status and timelines of RevMed-supported IME programs. This role requires strong program ownership, sound judgment, operational and analytical capabilities, attention to detail, and the ability to independently drive complex cross-functional initiatives in a fast-paced and evolving environment. Key responsibilities will include:

• Serve as the operational owner of Revolution Medicines' external funding program, including Independent Medical Education (IME), medical and patient advocacy sponsorships, memberships, corporate agreements, and charitable donations, ensuring scalable, consistent, and compliant execution across funding mechanisms.