Scientist
US$136,500 – US$221,000 / yr base salary
Posted 9 Sep 2026
Advertised as “Scientist / Senior Scientist, Membrane Biochemistry”
BranchFactor Summary
The original posting with the fluff stripped out
- Management level
- Individual contributor
| Base salary | US$136,500 – US$221,000 / yr |
|---|
Our Mission
Our mission is to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and the disabilities that can occur throughout life.
For more information, see our website at altoslabs.com.
Our Value
Our Single Altos Value: Everyone Owns Achieving Our Inspiring Mission.
Diversity at Altos
Altos Labs has been named one of the Top 3 Biotech Companies and ranked for the second year on the Forbes 2026 Best Startups in America list. At Altos, exceptional scientists and industry leaders from around the world work together to advance a shared mission. Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives. We are all accountable for sustaining a diverse and inclusive environment.
What You Will Contribute To Altos
As an individual contributor and Scientist in Discovery Science, you will advance Altos' scientific programs on brain aging and neurodegeneration using lipid and protein biochemistry approaches. The ideal candidate is an expert in membrane and lipid biology with experience purifying and structurally characterizing transmembrane or peripheral membrane-binding proteins. You will design and implement workflows that include construct design, expression and purification from mammalian recombinant sources, chromatography purification, membrane reconstitution, and vitrification for electron microscopy. You will also carry out biochemical activity assays and characterize biophysical properties of purified proteins, including hydrodynamic radius, binding kinetics, protein stability, and oligomerization. Experience with mass spectrometry, NMR, or X-ray crystallography of lipid-protein interactions is also of interest but not required. This position is in the Frost group at Altos Labs' Bay Area campus.
Responsibilities
- Design expression constructs and perform recombinant cell culture for membrane protein and membrane-associated protein purification and characterization.
- Evaluate the purity, stability, and physical properties of purified proteins.
- Develop new protein activity assays and establish SOPs.
- Coordinate with CROs for material generation and analysis.
Who You Are
Minimum qualifications
- PhD in a related field, such as Biochemistry, Chemistry, Biophysics, or Structural Biology
- Demonstrable understanding of biochemistry, including the use of electron microscopy for structural biochemistry.