Research Associate

Position Summary: 

The Research Associate will support Research and Development activities in the field of molecular biology, with a focus on the identification and verification of DNA methylation-based biomarkers and the development, optimization, and verification of epigenetic qPCR assays and ddPCR-based assays. The position involves the execution of laboratory experiments, processing of clinical study samples, analysis and documentation of experimental data, and support of laboratory quality and operational activities in a regulated environment.

Essential functions of the job include but are not limited to:

• Perform laboratory activities in accordance with approved SOPs, work instructions, and experimental protocols with appropriate guidance.
• Conduct laboratory experiments to support the identification and verification of DNA methylation-based biomarkers.
• Support the development, optimization, verification, and transfer of (epigenetic) qPCR- and ddPCR-based assays.
• Perform experimental quality control activities and support the qualification and release of plasmid standards and other critical reagents.
• Receive, prepare, process, and document clinical trial samples in accordance with defined procedures and study requirements.
• Perform epigenetic immune monitoring analyses, including bisulfite conversion and purification of DNA samples, qPCR analysis, data evaluation, and quality control.
• Analyze, interpret, document, and communicate experimental results to project scientists and team members.
• Identify technical issues, investigate deviations, and support troubleshooting and root cause analysis activities.
• Prepare reagents, controls, and laboratory materials required for routine and development activities.
• Operate and maintain laboratory automation and liquid handling systems.
• Perform routine equipment checks, maintenance, calibration support, and associated documentation activities.
• Maintain accurate, complete, and traceable laboratory records in accordance with applicable quality requirements.
• Support the preparation, review, and revision of SOPs, work instructions, protocols, reports, and other controlled documents.
• Participate in method evaluations, feasibility studies, and implementation of new laboratory technologies.
• Collaborate with scientists, project managers, and laboratory personnel to meet project timelines and milestones.
• Support laboratory organization, inventory management, ordering of consumables, and monitoring of laboratory supplies.
• Perform all activities in accordance with applicable health, safety, quality, and data integrity requirements.