Mechanical Engineer
Posted 6 Oct 2026
Advertised as “Sr Staff Mechanical Engineer ”
BranchFactor Summary
The original posting with the fluff stripped out
- Expected experience
- 8+ yrs
- Management level
- People management
- Employment
- On-Site
No salary listed for this role.
Field of studyMechanical Engineering
Study levelMaster's
Senior Staff Mechanical Engineer (Onsite in Wilsonville, OR)
Summary
We are seeking a Senior Staff Mechanical Engineer to design, build, and test our next-generation automated wet-lab instruments. Based primarily on-site in Wilsonville, OR with partial remote flexibility, this role requires occasional travel to Twist in South San Francisco, CA and to vendor locations.
Responsibilities:
- Use SolidWorks to design multiple instruments that integrate liquid handling, consumable handling, imaging & robotics that meet or exceed System & Hardware requirements
- Manage and use SolidWorks AI Agents to create new hardware designs leveraging parts & assemblies already in Twist’s PDM environment
- Specify all hardware (off-the-shelf and custom) for the instruments
- Work with other team members to develop and refine requirements
- Perform tolerance analysis as needed
- Support contract manufacturers and vendors as the Mechanical Technical Lead for your designs
- Work with other team members to execute and support Factory and Site Acceptance Testing
- Compile content and hold multiple design reviews as needed
- Use SolidWorks to design & build test fixtures as needed to de-risk concept features or test sub-systems
- Support Process Systems Engineers as needed during Concept Development and all other project phases
- Provide system fluidics and electrical design documentation
- Build, debug, calibrate, and verify the instruments with help from technicians and Process System Engineers
- Create full models, part files, part drawings, assembly drawings & a BOM for the System
- Maintain full design control and release via 3D- Experience (Dassault Systèmes)
- Order & track parts for system builds
- Provide updated designs for obsolete parts
- Lead hardware design for next-generation custom instrumentation, from concept and feasibility through post-production support.
- Provide concept architectures for Roadmap development
Required Skills:
- 12+ years of experience as a Senior Mechanical Engineer(or higher) and a 4-year degree in mechanical engineering, or 8 years of experience as a Senior Mechanical Engineer (or higher), with a graduate degree in mechanical engineering
- Expert in SolidWorks, with a proven record of delivering end-to-end design packages, complete engineering documentation, and fabrication-ready deliverables.
- Lead Mechanical Engineer of at least 2 benchtop or larger instruments that went into Production