Clinical Operations Director
US$250,000 – US$311,000 / yr base salary
Posted 1 Oct 2026
Advertised as “Senior Director, Clinical Operations”
BranchFactor Summary
The original posting with the fluff stripped out
- Expected experience
- 15+ yrs
- Management level
- People management
- Employment
- On-Site
| Base salary | US$250,000 – US$311,000 / yr |
|---|
Field of studyHealth-related studies, Scientific Studies
Study levelBachelor's
Study levelMaster's or higher
About Xaira Therapeutics
Xaira is an innovative biotech startup focused on leveraging AI to transform drug discovery and development. The company is leading the development of generative AI models to design protein and antibody therapeutics, enabling the creation of medicines against historically hard-to-drug molecular targets. It is also developing foundation models for biology and disease to enable better target elucidation and patient stratification. Collectively, these technologies aim to continually enable the identification of novel therapies and to improve success in drug development. Xaira is headquartered in the San Francisco Bay Area, Seattle, and London.
Position summary
Xaira Therapeutics is seeking an Executive Director, Clinical Operations to establish and lead the company’s clinical operations function as its first programs move from IND into the clinic. Reporting to the Vice President, Head of Early Development, this individual will be accountable for the operational strategy, delivery, quality, and cost of Xaira’s clinical portfolio.
This is a founding functional leadership role. The Executive Director will determine which capabilities Xaira builds internally and which are delivered through partners, establish the processes, systems, and governance required to support that model, and hire and develop the team. The role carries full accountability for study delivery from start-up through database lock while the function is being built, and requires a leader who is comfortable setting strategy and executing directly in the same week.
Clinical operations at Xaira works closely with the science, the AI and data organization, and senior leadership. The Executive Director will translate development plans, biomarker strategies, and patient selection approaches into studies that can be executed well, and will shape how Xaira applies clinical data, analytics, automation, and emerging AI tools to trial planning and delivery.
Key responsibilities
Functional leadership and operating model
- Serve as head of clinical operations, accountable for the operational strategy, delivery, and performance of Xaira’s clinical portfolio.
- Define the clinical operations operating model, including which capabilities are built internally and which are provided through partners, and establish the processes, governance, systems, and resourcing required to support it.
- Hire, lead, and develop the clinical operations team across trial management, study start-up, site management, and clinical supply coordination, and manage individual and collective performance.
- Establish functional metrics and management reporting covering timelines, enrollment, spend, quality, and risk, and present plans and material updates to R&D leadership and governance forums.