Director, Pharmacokinetics & Bioanalysis

About the Role

As Director, Pharmacokinetics, you'll shape the scientific and strategic direction of pharmacokinetics, drug metabolism, bioanalysis, and translational PK/PD across our entire portfolio. Working at the intersection of discovery, nonclinical development, clinical development, and regulatory strategy, you'll generate the PK insights that move programs forward — and the decisions that matter most to patients.

You'll design pharmacokinetic strategies tailored to each stage of development, lead internal and external activities, and partner closely with cross-functional teams to guide candidate selection, clinical dose planning, and regulatory submissions — turning scientific rigor into real progress for patients.

Let’s talk about how you’ll make an impact:

• Serve as Tarsus’s expert in pharmacokinetics and DMPK, shaping strategy across every program.
• Architect and drive PK, DMPK, bioanalytical, and translational PK/PD strategies that carry programs from early discovery all the way through clinical development.
• Design, lead, and interpret pharmacokinetic, metabolism, disposition, bioanalytical, and PK/PD nonclinical studies.
• Drive human PK projections, dose and regimen selection, and interpretation of emerging clinical data.
• Select and lead CROs, laboratories, consultants, and other external partners — assuring study quality, data integrity, and timelines.
• Review study protocols, reports, and datasets, identify pharmacokinetic and drug-metabolism risks early, and chart the development strategies.
• Author and review the pharmacokinetics, bioanalytical, and related sections of regulatory documents — including INDs, CTAs, investigator brochures, and briefing documents.
• Represent Pharmacokinetics on cross-functional project teams and governance forums, translating complex science into clear, actionable recommendations leadership can act on.
• Oversee the deployment, standardization, and routine execution of Phoenix WinNonlin and related modeling platforms for data analysis.

Driving Innovation, Inside and Out:

• Partner with our Innovation Lab and Business Development team to evaluate new assets, surfacing the risks and opportunities that shape what we pursue next.
• Scout and bring in new methods, AI technologies, and external capabilities that sharpen pharmacokinetic prediction, accelerate development, and improve the quality of every program decision.
• Cultivate strong scientific relationships, inside Tarsus and out, that push development forward.

Factors for Success: