Director, Viral Downstream Process Development

About us:

Our purpose at Dispatch is to help create a world where all cancer patients can be cured. We’re humbled by the opportunity to work together as a team on some of the most pressing medical challenges of our time. 

To achieve our purpose, we are dedicated to engineering a universal treatment across solid tumors. We’re committed to the development of novel therapies, leveraging first-in-class technologies in viral vectors, universal targets, and novel cytokine biology. Our therapeutic approach has the potential to enable us to treat significant numbers of cancer patients and make a real and lasting impact on the world. 

Our company was founded on pioneering work carried out in the laboratories of Dr. Carl June (University of Pennsylvania), Dr. Kole Roybal (University of California, San Francisco), Dr. Christopher Garcia (Stanford University) and Dr. Andy Minn (Memorial Sloan Kettering Cancer Center).

At our company, you would become one of our early team members— not only playing a role in meeting our ambitious mission but also building our thriving culture.  We are determined to deliver with urgency to discover new solutions and we always stay dedicated to scientific rigor; we have an ownership mindset because each and every one of us is integral to our success.  Collaboration is core for us because we believe that by bringing people together with diverse perspectives, we make a stronger whole.  And, we show we care about our work and each other by sharing feedback - ultimately in service of our vision to empower people to continue forward with their lives – cancer free. 

The role:

The (Associate) Director will serve as the downstream processing expert working closely with CDMOs to generate lentivirus and adenovirus products.  Reporting into the Vice President of Process Development, this individual will also be responsible for building out the internal downstream purification capabilities within process development to support scale up and scale down.

Key responsibilities:

• Oversee planning and execution of tech transfers, development and scale up of viral products being manufactured at CDMOs
• Serve as the downstream subject matter expert on both internal and external (CDMO, equipment suppliers, etc.) teams
• Build out internal downstream capabilities by identifying/procuring scale down models for process development
• Design and execute studies to identify critical process parameters and optimize process setpoints across the clarification, Tangential Flow Filtration (TFF), chromatography and sterile filtration steps
• Responsibility for execution, data review, analysis, and maintaining accurate and detailed lab notebooks