CMC Project Management

The Position

Join Maze Therapeutics as our Associate Director, CMC Project Management. In this highly visible role within Technical Operations, you will drive cross-functional planning and execution across our pipeline programs while managing development and manufacturing timelines in collaboration with our CMOs. Reporting to the VP, Technical Operations, you will partner closely with CMC, Quality, and key internal stakeholders to enable program milestones, support regulatory success, and ultimately help bring potential medicines to patients. 

The Impact You’ll Have

• Provide end-to-end CMC project management support across the drug development lifecycle. 

• Lead cross-functional teams (Chemical Development, Pharmaceutical Development, CMC Analytical, QA, CMC Regulatory, and Clinical Supply Chain) to plan and execute CMC activities aligned with corporate goals. 

• Serve as the point of contact to facilitate the meeting discussions with the CMOs and follow up on the action items. 

• Own risk management for assigned programs — establishing risk registries, identifying and mitigating risks, and escalating issues before they impact timelines or objectives. 

• Serve as the primary CMC project management point of contact to collaborate with the Program Management team, maintaining full command of CMC scope, status, and key risks while coordinating interdependencies across workstreams. 

• Facilitate governance and decision-making by preparing proposals, analyses, and recommendations for senior leadership review, and resolving cross-team conflicts that could impede progress. 

• Contribute to the planning and preparation of regulatory filings (e.g., IND, IMPD, etc.) in close partnership with Regulatory CMC and other functional teams. 

• Drive clear, consistent communication through dashboards, status reports, and meeting operations (agendas, minutes, action-item follow-up) for stakeholders ranging from project teams to senior leadership. 

• Cultivate strong working relationships across functions and with external partners to foster a collaborative, high-performing team environment and enable timely issue resolution. 

• Champion continuous improvement of project management processes, tools, and governance frameworks, and support program-level budget tracking and financial forecasting. 

As an Associate Director, we also expect our leaders to demonstrate the following Leadership Competencies:

Leadership Competencies