Medical Science Liaison

Olema Oncology is a clinical-stage biopharmaceutical company committed to transforming the standard of care and improving outcomes for patients living with breast cancer and beyond. With our transformation into a fully integrated oncology company well underway, it’s an exciting time to be part of Team Olema. 

Our lead product candidate, palazestrant, is a novel, orally available complete estrogen receptor antagonist (CERAN) and selective estrogen receptor degrader (SERD) currently in two pivotal Phase 3 clinical trials. We expect top-line data from OPERA-01, our ongoing Phase 3 trial of palazestrant as a monotherapy in patients with second- or third-line ER+/HER2- metastatic breast cancer (MBC), in Q1 2027 which, if positive, could lead to our first potential approval and commercial launch in 2028. OPERA-02, our Phase 3 trial of palazestrant in combination with ribociblib in patients with frontline ER+/HER2- MBC, is enrolling patients. Together with its mechanism of action, pharmacokinetic properties, and the potential to demonstrate activity in both ESR1 wild-type and mutant tumors, palazestrant could transform the metastatic breast cancer treatment paradigm and provide access to a $15 billion global market opportunity. 

Our follow-on product candidate, OP-3136, is a potent KAT6 inhibitor with the potential to generate further value and meaningfully impact the metastatic breast cancer treatment landscape – particularly in combination with palazestrant. We recently presented encouraging Phase 1 monotherapy data from this program across multiple solid tumor types, are advancing patient enrollment in the ongoing combination arms in MBC, and expect to initiate a Phase 1 study of OP-3136 in combination with Bayer’s darolutamide in metastatic castration-resistant prostate cancer by the end of this year. 

Aspiring to transform the metastatic treatment paradigm is an ambitious endeavor that requires a resolute approach to developing better therapies and passionate colleagues dedicated to helping the patients we serve feel better, longer. Team Olema possesses a deep commitment to a shared purpose, the sustained pursuit of excellence, cultivating the courage required to advance our programs, the drive to succeed, and a collective capacity for adaptability through learning, growth, and evolution. We are a small group of nimble self-starters who bring consistency in our quest for the extraordinary every single day. 

If you’re ready to be part of a tenacious, courageous, agile, and growing team, join us in making a profound impact, together – for our patients, for your career, and for what’s beyond.  

About the Role >>> Medical Science Liaison/Senior Medical Science Liaison, Southeast Region 

As the Medical Science Liaison/Senior Medical Science Liaison reporting to the Director, Medical Science Liaison, you will serve as a scientific expert and external representative for Olema. You will engage with key opinion leaders and healthcare providers to facilitate scientific exchange, communicate medical and clinical information, and support Olema's medical affairs objectives.  

This is a field-based role (Southeast Region) that requires 50% travel. 

Your work will primarily encompass: 

• Identify, connect, cultivate and maintain relationships with key opinion leaders, healthcare professionals and researchers in both academic and community centers within the assigned territory  
• Develop and execute territory engagement plans that aligned with medical affairs strategies to optimize impact in the field 
• Provide medical and scientific insights to internal stakeholders to inform product development and strategy 
• Facilitate and support new and ongoing clinical research in collaboration with medical and clinical operations teams (company-sponsored trials, investigator-initiated studies, and other collaborative initiatives)
• Serve as a trusted scientific and medical resource, providing accurate and updated information about Olema therapies and research externally  
• Conduct medical education programs and presentations to healthcare professionals as needed to relay information about Olema’s products and research  

And will also include: 

• Maintain up-to-date knowledge of developments in breast cancer research, treatment options, and disease management
• Professionally represent Olema at select medical and scientific conferences and meetings 
• Serve as scientific resource to commercial partners, as appropriate, to support activities 

Ideal Candidate Profile >>> 

A love of challenging, important work. We are a pragmatic team, driven to imagine and develop meaningful therapies for improving lives. All employees within our company play a unique and crucial role in our success, both in accomplishing our mission and building a positive company culture. As such, we are looking for someone with the right combination of knowledge, experience, and attributes for this role. 

Knowledge: 

• Doctorate degree (PharmD or PhD) required 
• Oncology therapeutic expertise required​ 
• Strong analytical skills demonstrating the ability to identify and understand complex issues/problems  
• Strong communication and presentation skills required 

Experience: 

• Minimum of 3 years of medical affairs or field medical experience with a verifiable record of high performance 
• Prior experience in solid tumors required with breast cancer experience strongly preferred 
• Clinical trial development and drug launch experience strongly preferred 
• Field medical experience within the Southeast region strongly preferred 

Attributes: 

• Simplifying complex information into clear, concise messages to effectively communicate the company story 
• Excellent communication skills – written, verbal, presentation, interpersonal 
• Serving in a high-visibility role and making public presentations to a variety of audiences 
• Ability to work in cross-functional teams with internal stakeholders 
• Anticipating needs, meeting tight deadlines, being proactive, and exercising independent decision-making 
• Managing the communication of sensitive and confidential information 
• This is a role where judgement, tact, flexibility and resourcefulness are key 
• Strong relationship-building and negotiating skills 
• Highly organized with an attention to detail and ability to meet timelines in a fast-paced environment 
• Strong project management skills; can work on multiple projects simultaneously and effectively prioritize workload 

Base pay offered may vary depending on location, market, job related knowledge, skills and capabilities, and experience. The total compensation package for this position also includes equity, bonus, and benefits.

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Important Information >>>

We provide equal opportunity to all employees and applicants for employment and believe that great ideas and discoveries come from a mix of expertise, background, and experience. Olema is building a culture where the value of difference is celebrated.

We offer a competitive compensation and benefits package, seeking to provide an open, flexible, and friendly work environment to empower employees and provide them with a platform to develop their long-term careers. A Summary of Benefits is available for all applicants.

Please note: Olema doesn’t accept agency resumes and is not responsible for any fees related to unsolicited resumes. Thank you.

Fraud Alert:  We are aware of employment scams where individuals pose as representatives of Olema Oncology and make false use of our company name to defraud job seekers. To protect yourself, please note that Olema’s official email addresses end in @olema.com. Our official corporate website is olema.com; our careers page is olema.com/careers; our LinkedIn page is linkedin.com/company/olema-oncology. Please visit these links for official information from Olema. Communication from any other variant is fraudulent. Olema does not conduct interviews via text message/messaging platforms, will not ask you to download anything as part of your interview, will never request any form of payment, provide upfront payments of any kind, and does not make job offers without an in-person interview.