Commercial Executive Operations Manager

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.

Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.

The Opportunity:

Revolution Medicines is establishing its European headquarters and expanding its presence across the CNE (Central, Northern, Eastern Europe) region. The Manager Commercial  Execution Ops CNE Region role leads the execution of high-complexity, cross-functional initiatives that ensure operational readiness, governance, and alignment across the European region. Serving as an operational support to the VP, General Manager CNE Region, this individual drives the design and implementation of scalable frameworks that enhance business integration and cross-regional collaboration. The ideal candidate thrives in a dynamic, fast-paced environment, demonstrates strong business acumen, and can build trusted partnerships across leadership teams and global functions.

Key responsibilities include:

• Assist CNE leadership team, cross-functional stakeholders and leaders to execute complex, crossfunctional initiatives across CNE operations.

• Support and maintain integrated governance frameworks and ensure strategic alignment with country, global and regional priorities.

• Own a fast paced regional calendar, managing strategic meetings across time zones.

• Lead planning and execution of internal CNE events, including annual kick-offs and quarterly cycle meetings.

• Lead organization of monthly CNE Leadership Team meetings and CNE governance meetings, including agenda setting, minute taking, follow up tracking and logistics.

• Work in close collaboration with other project coordinators and operational team members in European Commercialization to ensure a connected and engaged team.

• Plan and execute international travel itineraries including flights, ground transport, visas, accommodations, and contingency planning. Ensure seamless transitions between engagements and proactive resolution of travel disruptions.

• Ensure operational excellence, budget tracking, transparent reporting and documentation integrity.