Commercial Executive Operations Manager

Revolution Medicines is a global, commercial-state oncology company dedicated to discovering, developing and delivering innovative medicines for patients with RAS-addicted cancers. Leveraging its differentiated RAS(ON) tri-complex inhibitor platform, the company is advancing a broad, integrated portfolio of oral RAS(ON) inhibitors designed to directly target the active, cancer-driving state of RAS. Founded on rigorous scientific inquiry and a willingness to challenge long-held assumptions, Revolution Medicines is committed to changing the trajectory of disease for patients with RAS-addicted cancers worldwide.

Our people are united by a shared way of working: follow the science, challenge assumptions, act with urgency and hold ourselves to a high standard of rigor—all in service of patients.

The Opportunity: 

Revolution Medicines is establishing its European headquarters and expanding its presence across Spain and Portugal. The Manager Commercial Execution Ops role leads the execution of high-complexity, cross-functional initiatives that ensure operational readiness, governance, and alignment across the European region. Serving as an operational support to the VP, General Manager Spain and Portugal, this individual drives the design and implementation of scalable frameworks that enhance business integration and cross-regional collaboration. The ideal candidate thrives in a dynamic, fast-paced environment, demonstrates strong business acumen, and can build trusted partnerships across leadership teams and global functions. 

Key responsibilities include: 

• Assist Spain and Portugal leadership team, cross-functional stakeholders and leaders to execute complex, cross functional initiatives across Spain and Portugal operations. 

• Support and maintain integrated governance frameworks and ensure strategic alignment with country, global and regional priorities. 

• Support and follow up of leadership team meetings.

• Lead organization of monthly Spain and Portugal Leadership Team meetings and Spain and Portugal governance meetings, including agenda setting, minute taking, follow up tracking and logistics. 

• Work in close collaboration with other project coordinators and operational team members in European Commercialization to ensure a connected and engaged team. 

• Plan and execute international travel itineraries including flights, ground transport, visas, accommodations, and contingency planning. Ensure seamless transitions between engagements and proactive resolution of travel disruptions. 

• Ensure operational excellence, budget tracking, transparent reporting and documentation integrity. 

• Lead coordination of internal contract management and purchasing across functions and affiliates, ensuring alignment with Legal, Compliance and Finance governance.