IT Operations Manager

ABOUT eGENESIS

eGenesis is a clinical-stage biotechnology company developing human-compatible engineered organs to address the severe global organ shortage. The Company’s proprietary genome engineering platform enables extensive, multiplex gene edits to remove key biological barriers, add protective human transgenes, and inactivate endogenous retroviruses. EGEN-2784, a genetically engineered porcine kidney, is the Company’s lead program and is currently being evaluated in a multi-patient Expanded Access study at MGH. eGenesis is headquartered in Cambridge, MA.    At eGenesis, our core values—innovation, collaboration, compassion, resilience, and passion—are at the center of how we work. We engineer hope and bring passion to everything we do. We collaborate and learn from one another, combining diverse expertise to tackle complex challenges. We innovate boldly, pushing boundaries and science to new heights. where no pig organ has gone before. With resilience, we navigate challenges and celebrate progress together. And in all we do, we lead with compassion—for our patients, our people, and our pigs.

POSITION SUMMARY

eGenesis is looking for a Manager, IT Operations, based in our Cambridge, MA office with three days per week onsite, to run day-to-day technology operations across our four sites in Massachusetts, Wisconsin and Indiana. You will report to the Associate Director, Information Technology & Cybersecurity, and will own IT service delivery, endpoint and identity management, site infrastructure, and the performance of our managed service providers and support vendors. Occasional travel to our other sites is expected.

This is a hands-on role. You will administer core systems and work escalated issues yourself, and you will also direct our external partners and hold them to their service commitments. Employees at every site should get fast, effective support, and our operations have to hold up to the standards of a regulated environment — our labs and clinical programs depend on this infrastructure running well.

The role includes participation in off-hours incident response for critical outages and occasional planned maintenance outside business hours.

PRIMARY RESPONSIBILITIES

• Lead day-to-day IT operations and service delivery across all four eGenesis sites
• Manage the service desk in Freshservice, including queue management, prioritization, escalation handling, and quality of support
• Direct the work of managed service providers and support vendors, monitor vendor SLAs, and manage escalations through resolution
• Administer Microsoft 365, Entra ID, and Intune, including device compliance and security policies, conditional access, application deployment, and license management